Androgens in maternal vascular and placental function: implications for preeclampsia pathogenesis
نویسندگان
چکیده
منابع مشابه
Vascular Medicine Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension
Background—Preeclampsia is a life-threatening pregnancy syndrome of uncertain origin. To elucidate the pathogenesis, we evaluated the temporal relationships between changes in vascular function and circulating biomarkers of angiogenic activity before and after the onset of preeclampsia and gestational hypertension. Methods and Results—Maternal mean arterial pressure, uterine artery pulsatility ...
متن کاملAndrogens and Vascular Function
It is widely recognized that vascular function is modulated by the endocrine system. So it is known that hormones as aldosterone, renin-angiotensin II system, thyroids hormones, oxitocine, ghrelin, vasopressine, etc exert action on the vascular tone (Axelband et al., 2011; Nguyen & Touyz, 2011; Szmydynger-Chodobska et al., 2011; Tesauro et al., 2010;). Regarding sex hormones, epidemiological st...
متن کاملMaternal Vascular Physiology in Preeclampsia.
Preeclampsia is a systemic syndrome that occurs during pregnancy and postpartum and affects 3% to 8% of pregnancies. It is one of the leading causes of maternal and neonatal mortality and morbidity worldwide. The American College of Obstetricians and Gynecologists and the International Society for the Study of Hypertension in Pregnancy have set the following criteria for the clinical diagnosis ...
متن کاملAndrogens, ageing and vascular function.
We will never be perfect in achieving a diagnosis in every patient, and the challenge of geriatrics is how difficult it can be in some patients, and indeed, whether it is appropriate in others. An audit of our own ill-defined diagnoses showed that re-admission rates, at 1 month, were 10%, very similar to our better defined patients, and the great majority did not return to hospital within the n...
متن کاملVascular function in preeclampsia.
Preeclampsia is a multisystem disorder peculiar to human pregnancy. It occurs in 4-5% of all pregnancies and remains a leading cause of maternal and neonatal mortality and morbidity. The pathophysiology of this syndrome is not fully understood. Two stages of vascular dysfunction seem to be involved. In the early stage suboptimal development of the placenta and a hemodynamic maladaptation to pre...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Reproduction
سال: 2018
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-18-0278